Tracking-free mean square displacement analysis of molecular dynamics.

Nature protocols · 2026-11-03 · 综述

Here we describe a protocol for image-derived mean squared displacement (iMSD) analysis, a fluctuation-based technique to quantify the average spatiotemporal dynamics of subcellular structures-such as proteins, organelles and nanoparticles-in living cells. Unlike single-particle tracking, which relies on discrete object localization and trajectory reconstruction, iMSD computes the spatiotemporal autocorrelation funct…

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Ferri G, Digiacomo L, Digman MA 等

本文摘自《每日前沿研究简报 · 2026-11-05》「化学信息 / 药物发现」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。