dsRNA: mechanisms of gene expression regulation, disease pathogenesis, and therapeutic potential.

RNA biology · 2026-11-03 · 综述

Double-stranded RNA (dsRNA) has long been recognized as a viral pathogen-associated molecular pattern that activates innate immunity. However, dsRNA is increasingly recognized as a regulatory RNA species involved in RNA homeostasis, gene expression, and cell fate determination. In this review, we discuss canonical dsRNA-dependent mechanisms, including RNA interference (RNAi), with particular emphasis on nuclear RNAi,…

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Liu S, Zhe C, Hou J 等

本文摘自《每日前沿研究简报 · 2026-11-05》「生物信息 组学」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。