Urinary ubiquitin-specific protease 2 (USP2) as a diagnostic biomarker for chronic kidney disease: an integrated multi-o

Renal failure · 2026-11-04 · 期刊论文

Chronic kidney disease (CKD) is associated with progressive metabolic and molecular dysregulation, yet reliable noninvasive biomarkers remain limited. Ubiquitin-specific protease 2 (USP2) regulates transforming growth factor-β signaling and ferroptosis through lactylation-dependent deubiquitinase activity, but its clinical relevance in CKD remains unclear. We enrolled 25 patients with CKD and 10 healthy controls and …

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Wang X, Xie Y, Duan Q 等

本文摘自《每日前沿研究简报 · 2026-11-05》「生物信息 组学」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。