Microbial metabolites and MAMPs: orchestrators of intestinal stem cell function.

Gut microbes · 2026-11-04 · 综述

Intestinal stem cells (ISCs) are essential for maintaining and regenerating the intestinal epithelium. Recent studies have highlighted the critical role of the gut microbiota in regulating ISC function through diverse molecular signals, particularly microbial metabolites and microbe-associated molecular patterns (MAMPs). Microbial metabolites, such as short-chain fatty acids (SCFAs) and indoles, modulate ISC activiti…

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Shekhar S, Šrůtková D, Schwarzer M.

本文摘自《每日前沿研究简报 · 2026-11-05》「发育·再生·干细胞」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。