Synthetic nanobodies for drug discovery-Design, construction, optimization, and applications.

FEBS letters · 2026-11-04 · 综述

Nanobodies (Nbs) are single-domain antibody fragments derived from camelid heavy-chain-only antibodies (HCAbs). Nbs can be readily produced in microbial expression systems and are widely used as research tools while also being actively explored for diagnostic and therapeutic applications. Nbs are traditionally isolated from either immune libraries generated through camelid immunization or naïve libraries constructed …

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Xie Y, Tian Z, Wen Y 等

本文摘自《每日前沿研究简报 · 2026-11-05》「化学信息 / 药物发现」。本内容仅用于研究信息整理与科普交流，不构成医疗建议。